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KMID : 0191120180330470300
Journal of Korean Medical Science
2018 Volume.33 No. 47 p.300 ~ p.300
Psychiatric Manifestation in Patients with Parkinson's Disease
Han Ji-Won

Ahn Ye-Bin D.
Kim Won-Seok
Shin Cheol-Min
Jeong Seong-Jin
Song Yoo-Sung
Bae Yun-Jung
Kim Jong-Min
Abstract
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although its major manifestation is motor symptoms, resulting from the loss of dopaminergic neurons in the substantia nigra, psychiatric symptoms, such as depression, anxiety, hallucination, delusion, apathy and anhedonia, impulsive and compulsive behaviors, and cognitive dysfunction, may also manifest in most patients with PD. Given that the quality of life ? and the need for institutionalization ? is so highly dependent on the psychiatric well-being of patients with PD, psychiatric symptoms are of high clinical significance. We reviewed the prevalence, risk factors, pathophysiology, and treatment of psychiatric symptoms to get a better understanding of PD for improved management.
KEYWORD
Parkinson's Disease, Psychiatry, Depression, Psychosis, Impulse Control Disorder, Dementia
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